Biomarkers that have proven to be predictors of immunotherapy responses in melanoma patients have also been shown to be clinically relevant in breast cancer patients. Clinical cancer research..
This study found that this biomarker, a molecule called major histocompatibility complex class II protein (MHC-II), Immunotherapy Two types of benefits chest Cancer-Early triple-negative breast cancer (TNBC) and high-risk estrogen receptor-positive breast cancer (HR +) when expressed in breast cancer cells.
Immunotherapy may be prescribed immediately with chemotherapy for these breast cancers prior to surgery, but most patients do not need additional immunotherapy to achieve a therapeutic response. Without optimal biomarkers, clinicians have no reliable way to identify which patients need immunotherapy and which do not.
Clinical trials of MHC-II expression can protect breast cancer patients who do not require immunotherapy from possible treatment complications and additional costs. Immunotherapy is expensive and highly toxic. [Read more…] about Study identifies biomarker for breast cancer response to immunotherapy
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