In rodents with type 2 diabetes, a single surgical injection of a protein called fibroblast growth factor 1 can restore blood sugar levels to normal for weeks or months. Yet how this growth factor acts in the brain to generate this lasting benefit has been poorly understood.
Clarifying how this occurs might lead to more effective diabetes treatments that tap into the brain’s inherent potential to ameliorate the condition.
“Until recently, the brain’s ability to normalize elevated blood sugar levels in diabetic animals was unrecognized,” said Dr. Michael Schwartz, professor of medicine at the University of Washington School of Medicine and co-director of the UW Medicine Diabetes Institute. [Read more…] about The brain can induce diabetes remission in rodents, but how?