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How the brain’s blue spot helps us focus our attention

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The neurotransmitter noradrenaline regulates our brain’s sensitivity to relevant information

How can we shift from a state of inattentiveness to one of highest attention? The locus coeruleus, literally the “blue spot,” is a tiny cluster of cells at the base of the brain. As the main source of the neurotransmitter noradrenaline, it helps us control our attentional focus.

Synthesizing evidence from animal and human studies, scientists at the Max Planck Institute for Human Development and the University of Southern California have now developed a novel framework describing the way the blue spot regulates our brain’s sensitivity to relevant information in situations requiring attention.

Their findings have been published in an opinion article in the journal Trends in Cognitive Sciences. [Read more…] about How the brain’s blue spot helps us focus our attention

Exercise alters brain chemistry to protect ageing synapses

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When elderly people stay active, their brains have more of a class of proteins that enhances the connections between neurons to maintain healthy cognition, a UC San Francisco study has found.

This protective impact was found even in people whose brains at autopsy were riddled with toxic proteins associated with Alzheimer’s and other neurodegenerative diseases.

“Our work is the first that uses human data to show that synaptic protein regulation is related to physical activity and may drive the beneficial cognitive outcomes we see,” said Kaitlin Casaletto, PhD, an assistant professor of Neurology and lead author on the study, which appears in the January 7 issue of Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. [Read more…] about Exercise alters brain chemistry to protect ageing synapses

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    Is sitting always bad for your mind? A new study suggests maybe notIt's generally accepted health advice that adults of all ages should sit less, move more, and engage in regular exercise to feel better and reduce the risk of chronic diseases. However, when it comes to the brain and cognition, a new study of older adults from Colorado State University suggests…
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  • Human molecule blocking toxic forms of Parkinson's-related protein identified
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    Human molecule blocking toxic forms of Parkinson's-related protein identifiedThe death of neurons specialised in the synthesis of dopamine, one of the brain's main neurotransmissors, deteriorates the motor and cognitive capacities of those with Parkinson's disease. The loss of these neurons is related to alpha-synuclein aggregation. Recent studies show that oligomers, the initial aggregates of this protein, are the…
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Russian researchers present ultra-precise brain imaging tool

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A joint team from the Russian Quantum Center, Skoltech, and the Higher School of Economics has presented a novel supersensitive solid-state magnetometer operating at room temperature. The researchers for the first time used it to detect and record brain electrical activity with a technique called magnetoencephalography, which could become dozens of times cheaper with the new device. The paper was published in Human Brain Mapping.

High accuracy is a key advantage of magnetoencephalography (MEG) over other similar techniques used for studying the electrical activity of the brain. Biological tissues are transparent for magnetic fields. However, only a very limited number of laboratories around the world have MEG equipment, which uses either extremely cold liquid helium or high-temperature gas and is very expensive and difficult to manufacture.

A team from the Russian Quantum Center (RQC) developed a new sensor using yttrium-iron garnet films. This is the first solid-state supersensitive room-temperature magnetometer in the world. It is based on a quantum sensor and is capable of registering very weak or deep electrical sources in the brain. Owing to its wide dynamic range, the device requires less magnetic shielding, which means a lower cost of both the hardware and the entire research infrastructure. [Read more…] about Russian researchers present ultra-precise brain imaging tool

NYU Abu Dhabi researchers discover new findings on the evolution of galaxies

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Emirati national Aisha Al Yazeedi, a research scientist at the NYU Abu Dhabi (NYUAD) Center for Astro, Particle, and Planetary Physics, has published her first research paper, featuring some key findings on the evolution of galaxies.

Galaxies eventually undergo a phase in which they lose most of their gas, which results in a change into their properties over the course of their evolution. Current models for galaxy evolution suggest this should eventually happen to all galaxies, including our own Milky Way; Al Yazeedi and her team are delving into this process.

Commenting on the findings, Al Yazeedi said: “The evolution of galaxies is directly linked to the activity of their central supermassive blackhole (SMBH). However, the connection between the activity of SMBHs and the ejection of gas from the entire galaxy is poorly understood.

“Observational studies, including our research, are essential to clarify how the central SMBH can influence the evolution of its entire host galaxy and prove key theoretical concepts in the field of astrophysics.” [Read more…] about NYU Abu Dhabi researchers discover new findings on the evolution of galaxies

Motivation depends on how the brain processes fatigue

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How do we decide whether or not an activity which requires work is ‘worth the effort’? Researchers at the University of Birmingham & University of Oxford have shown that the willingness to work is not static, and depends upon the fluctuating rhythms of fatigue.

Fatigue – the feeling of exhaustion from doing effortful tasks – is something we all experience daily. It makes us lose motivation and want to take a break. Although scientists understand the mechanisms the brain uses to decide whether a given task is worth the effort, the influence of fatigue on this process is not yet well understood.

The research team conducted a study to investigate the impact of fatigue on a person’s decision to exert effort. They found that people were less likely to work and exert effort – even for a reward – if they were fatigued. The results are published in Nature Communications. [Read more…] about Motivation depends on how the brain processes fatigue

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  • Brain activity foreshadows changes in stock prices
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Study suggests scientists may need to rethink which genes control aging

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To better understand the role of bacteria in health and disease, National Institutes of Health researchers fed fruit flies antibiotics and monitored the lifetime activity of hundreds of genes that scientists have traditionally thought control aging.

To their surprise, the antibiotics not only extended the lives of the flies but also dramatically changed the activity of many of these genes. Their results suggested that only about 30% of the genes traditionally associated with aging set an animal’s internal clock while the rest reflect the body’s response to bacteria.

“For decades scientists have been developing a hit list of common aging genes. These genes are thought to control the aging process throughout the animal kingdom, from worms to mice to humans,” said Edward Giniger, Ph.D., senior investigator, at the NIH’s National Institute of Neurological Disorders and Stroke (NINDS) and the senior author of the study published in iScience. [Read more…] about Study suggests scientists may need to rethink which genes control aging

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Study shows how taking short breaks may help our brains learn new skills

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In a study of healthy volunteers, National Institutes of Health researchers have mapped out the brain activity that flows when we learn a new skill, such as playing a new song on the piano, and discovered why taking short breaks from practice is a key to learning.

The researchers found that during rest the volunteers’ brains rapidly and repeatedly replayed faster versions of the activity seen while they practiced typing a code.

The more a volunteer replayed the activity the better they performed during subsequent practice sessions, suggesting rest strengthened memories. [Read more…] about Study shows how taking short breaks may help our brains learn new skills

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Weight-loss maintainers sit less than weight-stable people with obesity

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People who are successful at weight-loss maintenance spend less time sitting during the week and weekends compared to weight-stable individuals with obesity, according to a paper published online in Obesity, The Obesity Society’s flagship journal. This is the first study to examine time spent in various sitting activities among weight-loss maintainers.

Prior findings from 2006 in the National Weight Control Registry indicated that weight-loss maintainers watched significantly less television than controls, but other sitting activities were not examined. In the current study, weight-loss maintainers did not significantly differ from controls in reported weekly sitting time spent watching television, but did differ in time spent in non-work-related time using a computer or video game.

Differences between the current study and National Weight Control Registry findings could reflect changes over the past 15 years in available electronic devices, including the rise in availability of computers and video games. Weight-loss maintainers and controls also did not appreciably differ in time spent sitting while reading or studying, traveling; or talking, texting and socializing. These could be considered more mentally active forms of sedentary behavior. [Read more…] about Weight-loss maintainers sit less than weight-stable people with obesity

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Press (re)play to remember – How the brain strengthens memories during sleep

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While we sleep, the brain produces particular activation patterns. When two of these patterns – slow oscillations and sleep spindles – gear into each other, previous experiences are reactivated. The stronger the reactivation, the clearer will be our recall of past events, a new study reveals.

Scientists have long known that slow oscillations (SOs) and sleep spindles – sudden half-second to two-second bursts of oscillatory brain activity – play an important role in the formation and retention of new memories.

But experts in the UK and Germany have discovered that the precise combination of SOs and sleep spindles is vital for opening windows during which memories are reactivated; helping to form and cement memories in the human brain. [Read more…] about Press (re)play to remember – How the brain strengthens memories during sleep

Head to toe: Study reveals brain activity behind missed penalty kicks

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Are penalty shots a soccer player’s dream or nightmare? What should be an easy shot can become a mammoth task when the hopes and fears of an entire nation rest on a player’s shoulders, leading them to choke under pressure.

Understanding the brain activity behind choking is the driving force behind a new study in open-access journal Frontiers in Computer Science.

The study is the first to measure brain activity during penalty shots in a soccer pitch environment. It finds that people who choked activated areas of the brain involved in long-term thinking, suggesting that they were overthinking the consequences of missing the shot. [Read more…] about Head to toe: Study reveals brain activity behind missed penalty kicks